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In patients with closed-head injuries, what may happen if the patient has hypercapnia?


A) High CO2 increases the risk of psychotic events.
B) High CO2 levels cause cerebral vasodilation and improved oxygenation.
C) Severe cerebral vasoconstriction results in anoxia and stroke.
D) Vasodilation causes increased intracranial pressure and possibly stops blood flow.

E) None of the above
F) A) and B)

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Both anemia and carbon monoxide (CO) poisoning can cause severe hypoxia, yet neither condition results in a major stimulation of breathing. Why is this so?


A) The peripheral chemoreceptors do not respond to low oxygen content.
B) Anemia and CO poisoning depress the peripheral chemoreceptors.
C) Anemia and CO poisoning depress the central chemoreceptors.
D) Anemia and CO cause stagnant hypoxia, not hypoxemia.

E) None of the above
F) A) and D)

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In the face of hyperoxia, what is the response of the peripheral chemoreceptors to hypercapnia?


A) There is a decreased drive to breathe.
B) There is an increased drive to breathe.
C) There is insufficient information.
D) There is virtually no response.

E) A) and B)
F) None of the above

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How should oxygen therapy be administered to chronically hypercapnic patients?


A) avoid giving any supplemental oxygen
B) give as much oxygen as possible (60% to 100%)
C) withhold oxygen until the patient is intubated
D) give as much oxygen as required to maintain adequate oxygenation

E) None of the above
F) All of the above

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Where are the peripheral chemoreceptors located? I.in the arch of the aorta II.in the bifurcations of carotid arteries III.on the ventrolateral surfaces of the medulla


A) I and II
B) I
C) II and III
D) I, II, and III

E) C) and D)
F) All of the above

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Which of the following is indirectly responsible for minute-to-minute control of breathing?


A) CO2 levels
B) HCO3- levels
C) lactate levels
D) O2 levels

E) None of the above
F) All of the above

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What stimulates the Hering-Breuer inflation reflex?


A) the DRG when it is time to end inspiratory efforts
B) the stretch of receptors at high lung volumes
C) the VRG when it is time for inspiration
D) very low lung volumes stimulate inspiration

E) C) and D)
F) A) and C)

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Biot's respiration is most frequently observed in patients with which of the following?


A) congestive heart failure
B) increased intracranial pressure
C) metabolic acidosis
D) peripheral nerve disorders

E) A) and B)
F) None of the above

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