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Once alkalosis has occurred, which of the following would you expect to happen?


A) increased respiratory rate
B) a plasma pH less than 7.40
C) retention of hydrogen ions by the kidney
D) increased renal reabsorption of bicarbonate ions
E) secretion of hydrogen ions by the kidney

F) B) and D)
G) C) and D)

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One difference between the plasma and interstitial fluid is that the plasma has significantly more _____ than interstitial fluid.


A) protein
B) bicarbonate
C) chloride
D) water volume
E) hydrogen ions

F) A) and D)
G) C) and E)

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What hormone regulates potassium levels, and how does it work?


A) Aldosterone; increases secretion of potassium
B) Aldosterone; increases reabsorption of potassium
C) ADH; increases secretion of potassium
D) ADH; increases reabsorption of potassium
E) ANH; increases reabsorption of potassium

F) A) and B)
G) C) and E)

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Which of the following regulatory mechanisms would be stimulated as a result of the increased osmolality that results from a Na+ level of 152 mEq/L?


A) increased urine output
B) an increased release of ADH
C) an increase in renin production
D) an increase in the secretion of aldosterone
E) a decreased release of ADH

F) A) and D)
G) None of the above

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Parathyroid hormone increases the activity of ___________ cells in bone and increases the rate of calcium ___________ in the kidney tubules.


A) osteoclast; reabsorption
B) osteoblast; reabsorption
C) osteocyte; reabsorption
D) osteocyte; secretion
E) osteoblast; secretion

F) C) and D)
G) A) and C)

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If the hydrogen ion concentration in the blood increases, bicarbonate ions act as buffers by


A) removing excess hydrogen ions from the plasma.
B) releasing hydrogen ions into the plasma.
C) dissociating into H+ and CO3-.
D) combining with chloride ions.
E) combining with hemoglobin.

F) A) and D)
G) A) and B)

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Hyperventilation of the lungs can lead to ______________________.


A) Respiratory acidosis
B) Respiratory alkalosis
C) Metabolic acidosis
D) Metabolic alkalosis
E) Respiratory shock

F) A) and B)
G) A) and E)

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Parathyroid hormone effects the


A) bones, heart, and blood.
B) kidney, liver, and spleen.
C) intestine, kidneys, and bone.
D) liver, stomach, and small intestine.
E) stomach, pancreas, and bone.

F) A) and C)
G) D) and E)

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The sensation of thirst results from


A) an increase in the plasma volume.
B) hypertension (increased blood pressure) .
C) stimulation of osmoreceptor cells in the hypothalamus.
D) a decrease in the osmolality of the extracellular fluid.
E) stimulation of baroreceptors.

F) B) and C)
G) A) and E)

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Mr. I.M.A. Wreck's plasma pH is 7.2. Which of the following indicates that the body is attempting to compensate and return the body pH to normal?


A) an increase in respiration rate
B) a decrease in respiration rate
C) no change in respiration rate

D) A) and B)
E) A) and C)

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Which of the following events occurs last?


A) release of renin by the kidney
B) release of aldosterone by the adrenal cortex
C) sodium reabsorption by the kidney tubules
D) angiotensinogen \rightarrow angiotensin I
E) angiotensin I \rightarrow angiotensin II

F) B) and C)
G) C) and E)

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The stimulus for secretion of atrial natriuretic hormone is increased


A) blood osmolality.
B) aldosterone production.
C) blood pressure in atria of heart.
D) blood pressure in kidney's afferent arterioles.
E) blood pressure in the ventricles of the heart.

F) C) and D)
G) A) and C)

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C

Which of the following is not a function of the carbonic acid/bicarbonate system?


A) Regulation of the pH of the intracellular environment
B) Regulating pH changes of the blood during exercise
C) Regulation of blood pH during elevated fat matabolism
D) Regulation of blood pH in coordination with the respiratory system
E) Regulation of blood pH in coordination with the kidneys

F) A) and C)
G) D) and E)

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Which of the following is most likely to happen to a group of students who relax by drinking a pitcher of their favorite beverage?


A) an increase in urine volume
B) an increase in urine osmolality
C) an increase in ADH production
D) increased aldosterone secretion
E) a decrease in urine volume

F) D) and E)
G) A) and E)

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Receptors sensitive to changes in the osmolality of extracellular fluid are the


A) baroreceptors.
B) chemoreceptors.
C) osmoreceptors.
D) pressoreceptors.
E) proprioreceptors.

F) A) and D)
G) D) and E)

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Extracellular fluid has a


A) higher protein content than intracellular fluid.
B) higher potassium content than intracellular fluid.
C) higher sodium content than intracellular fluid.
D) higher magnesium content than intracellular fluid
E) higher number of large organic molecules than intracellular fluid.

F) B) and D)
G) A) and D)

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C

Slight deviations from the normal concentration of ___________ ions can shut down metabolic pathways as well as alter the structure and function of other macromolecules.


A) hydrogen
B) potassium
C) sodium
D) phosphate
E) glucose

F) A) and B)
G) A) and E)

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Name the ion that commonly serves as a cofactor for intracellular enzymes, such as the sodium-potassium pump.


A) Magnesium
B) Calcium
C) Hydrogen
D) Carbonate
E) Phosphate

F) A) and E)
G) A) and D)

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Loss of a large volume of sweat will


A) decrease the hematocrit.
B) decrease ADH production.
C) increase the blood pressure.
D) increase the osmolality of body fluids.
E) decrease the osmolality of body fluids.

F) B) and C)
G) B) and D)

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D

Azetazolamide (Diamox) is a diuretic. It functions by blocking the activity of carbonic anhydrase inside kidney tubule cells. This slows the formation of carbonic acid. By slowing the formation of hydrogen ions in the cells of the tubule, sodium reabsorption is also slowed. This results in the diuretic effect. Select from the following list the possible side-effects of Azetazolamide. (1) acidosis (2) reduced movement of bicarbonate ion into the plasma (3) an alkaline urine is produced (4) respiration increases


A) 1, 4
B) 2, 3
C) 1, 2, 3
D) 2, 3, 4
E) 1, 2, 3, 4

F) D) and E)
G) A) and E)

Correct Answer

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