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Lymph exits a lymph node via the


A) efferent lymphatic vessels.
B) afferent lymphatic vessels.
C) cortical sinuses.
D) trabeculae.
E) lymphatic duct.

F) B) and E)
G) A) and B)

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When innate immunity is activated,


A) each exposure is very specific.
B) previous exposures are remembered.
C) each exposure produces the same response.
D) each exposure increases the strength of the immune response.
E) the second exposure does not produce a response.

F) None of the above
G) D) and E)

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Match the type of cell with its function. -mast cell


A) first cell to enter infected tissue
B) will become macrophage in tissue
C) lyses tumor and virus-infected cells
D) cell that increases in number during a parasitic infection
E) nonmotile cells in connective tissue that promote inflammation
,

F) A) and D)
G) B) and E)

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Match the term or description to the type of hypersensitivity. -anaphylaxis


A) immediate hypersensitivity
B) delayed hypersensitivity

C) A) and B)
D) undefined

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Match the term with the appropriate description. -histamine


A) lipids that cause smooth muscle relaxation and vasodilation
B) lymph nodules aggregated in the small intestinal wall
C) rounded epithelial structures found in the medulla of thymus
D) areas of a lymph node where lymphocytes divide
E) a chemical released from mast cells that causes vasodilation

F) A) and E)
G) A) and D)

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Tolerance is a state of


A) hypersensitivity.
B) transplant rejection.
C) unresponsiveness to antigens.
D) responding to self-antigens.
E) non-recognition of antigens.

F) D) and E)
G) A) and E)

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The thymus is where ____ mature and become functional immune cells.


A) pre-T cells
B) pre-B cells
C) macrophages
D) null cells
E) C cells.

F) B) and C)
G) A) and E)

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Lymph movement is assisted by


A) contraction of skeletal muscle.
B) contraction of smooth muscle in lymph vessel.
C) pressure changes in the thorax during respiration.
D) compression of lymphatic vessels.
E) All of these choices are correct.

F) C) and E)
G) C) and D)

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Stimulating the proliferation of cytotoxic T cells to destroy cancer cells is an example of


A) immunotherapy.
B) immunocompetence.
C) tolerance.
D) passive artificial acquired immunity.
E) passive natural acquired immunity.

F) A) and E)
G) A) and C)

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Which of the following organs does NOT contain lymphatic tissue?


A) liver
B) spleen
C) lingual tonsils
D) thymus
E) pharyngeal tonsils.

F) A) and C)
G) A) and D)

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Which of the following characteristics is/are most consistent with adaptive immunity?


A) constant response to each exposure
B) specificity
C) memory
D) increased response to second and subsequent exposures
E) specificity,memory and increased response to second and subsequent exposures

F) B) and C)
G) A) and B)

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A surface chemical that prevents microbial growth is


A) histamine.
B) leukotriene.
C) sebum.
D) kinin.
E) interferon.

F) D) and E)
G) B) and C)

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Lymphocyte activation can occur in several ways.However,in all cases


A) lymphocytes must recognize an antigen.
B) helper T cells are activated first and they then stimulate other cells.
C) antigen-presenting cells process the antigen and present it to the lymphocytes.
D) cytokines released by the antigen stimulate the lymphocyte response.
E) antigens must be able to recognize the lymphocytes.

F) A) and B)
G) A) and D)

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Adaptive immunity is stimulated by


A) antigens.
B) histamines.
C) antibodies.
D) complement.
E) plasma proteins.

F) A) and E)
G) C) and D)

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Which of the following cytokines is mismatched?


A) perforin - makes a hole in target cell membranes
B) alpha interferon - prevents viral replication
C) lymphotoxin - costimulator of T cells
D) interleukin 4 - plays a role in allergic reactions
E) TNF - activates macrophages and promotes fever

F) D) and E)
G) B) and C)

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Antibodies secreted in breast milk


A) are IgG antibodies.
B) are IgA antibodies.
C) provide natural active adaptive immunity.
D) include the cytokine interleukin 2.
E) promote inflammation.

F) C) and D)
G) All of the above

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The movement of leukocytes to the source of certain chemicals is called


A) chemotaxis.
B) opsonization.
C) chemoreception.
D) phagocytosis.
E) hemolysis.

F) B) and C)
G) B) and E)

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The effects of cell-mediated immunity are the result of activities of


A) B cells.
B) cytotoxic T cells.
C) macrophages.
D) dendritic cells.
E) helper T cells.

F) B) and E)
G) C) and D)

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Which of the following is a subpopulation of T cells?


A) cytotoxic
B) antigenic
C) cytokinetic
D) basophilic
E) antitoxic

F) B) and D)
G) A) and B)

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The HIV virus can be transmitted


A) only from males to other males.
B) during unprotected sexual intercourse.
C) by coughing or sneezing.
D) by contact with people at work.
E) by hugging an infected child.

F) A) and D)
G) D) and E)

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